Endocrine Abstracts

Oestrogens are formed in the ovary from androgen precursors which circulate at a higher concentration in the blood and have a greater production and secretion rate than oestrogens. Although the post menopausal ovary remains a source of testosterone (T) production there is a fall in total circulating androgens with age and this results from a combination of ovarian failure, decreasing adrenal secretion and peripheral conversion.This relative androgen deficiency is greater in wo...

Oestrogens are formed in the ovary from androgen precursors which circulate at a higher concentration in the blood and have a greater production and secretion rate than oestrogens. Although the post menopausal ovary remains a source of testosterone (T) production there is a fall in total circulating androgens with age and this results from a combination of ovarian failure, decreasing adrenal secretion and peripheral conversion.This relative androgen deficiency is greater in wo...

Postmenopausal hormonal therapy has been used to manage climacteric symptoms since the 1950’s. Several large observational studies suggested that the use of HRT may also have a role in the prevention of chronic conditions in the postmenopausal woman. In a Department of Health survey performed in 1998, 38% of women in England aged 45–54 years had used HRT. However over the past few years there has been a marked fall in prescribing rates due to the publication of sever...